Table 4.
Relationship of dietary intake to iron deficiency in HF patients with ferritin ≥30 ng/ml (logistic regression model).
| Model 1 | Model 2* | Model 3† | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Group | Dietary intake | OR | 95% CI | P-value | OR | 95% CI | P-value | OR | 95% CI | P-value |
| Ferritin <100 ng/ml | Iron | 1.01 | 0.77, 1.32 | >0.9 | ||||||
| Total folate | 0.78 | 0.63, 0.96 | 0.022 | 0.80 | 0.65, 0.99 | 0.042 | 0.80 | 0.65, 1.00 | 0.047 | |
| ID (heart failure guideline criteria) | Iron | 0.96 | 0.71, 1.30 | 0.781 | ||||||
| Total folate | 0.83 | 0.60, 1.15 | 0.249 | |||||||
| Ferritin <300 ng/ml | Iron | 0.95 | 0.85, 1.07 | 0.398 | ||||||
| Total folate | 0.91 | 0.79, 1.04 | 0.146 | |||||||
| TSAT <20% | Iron | 0.99 | 0.80, 1.23 | >0.9 | ||||||
| Total folate | 1.02 | 0.76, 1.37 | 0.893 | |||||||
| Serum iron ≤13 μmol/L | Iron | 1.10 | 0.90, 1.36 | 0.334 | ||||||
| Total folate | 1.01 | 0.78, 1.32 | >0.9 | |||||||
| Serum iron ≤10 μmol/L | Iron | 1.17 | 0.95, 1.45 | 0.137 | ||||||
| Total folate | 1.12 | 0.88, 1.43 | 0.337 | |||||||
ALT, alanine transaminase; AST, aspartate transaminase; CI, confidence interval; HF, heart failure; ID, iron deficiency; OR, odds ratio; TSAT, transferrin saturation.
*
Model 2: Model adjusted for race, ln (ALT), ln (AST), hemoglobin.
†
Model 3: Model 2 + gender.