Table 3.
Minimum inhibitory concentration (MIC) values of imipenem and meropenem for carbapenem-resistant Enterobacterales isolates.
| Isolates | Antibiotic | R (%)1 | 95% CI | MIC for resistant isolates (µg/mL)2 | |||
|---|---|---|---|---|---|---|---|
| MIC50 | MIC90 | GM | Range | ||||
| Klebsiella spp. (n = 96) | Imipenem | 58 (60.4) | 49.9 – 70.3 | 8 | 16 | 6.6 | 2 - 16 |
| Meropenem | 44 (45.8) | 35.6 – 56.3 | 2 | 128 | 4.9 | 1 - 128 | |
| E. coli (n = 13) | Imipenem | 7 (53.8) | 25.1 - 80.8 | 8 | 16 | 6.4 | 4 - 16 |
| Meropenem | 3 (23.1) | 5.0 - 53.8 | 2 | 4 | 6.5 | 1 - 4 | |
| Total (n = 109) | Imipenem | 65 (59.6) | 49.8 – 68.9 | 8 | 16 | 6.6 | 2 - 16 |
| Meropenem | 47 (43.1) | 33.7 – 52.9 | 2 | 128 | 4.9 | 1 - 128 | |
1R: number of resistant isolates.
2MIC50, MIC values that inhibited 50% of the isolates; MIC90, MIC values that inhibited 90% of the isolates; GM, geometric mean.