Table 6.
Relationship between carbapenem resistance genes and MICs of imipenem and meropenem against isolates.
| Paramter1 | MIC of IPM (µg/mL) | MIC of MEM (µg/mL) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| KPC | VIM | NDM | IMP | OXA-48 | OXA-181 | KPC | VIM | NDM | IMP | OXA-48 | OXA-181 | |
| GM | 7.5 | 6.9 | 7.7 | 6.9 | 7.1 | 6.3 | 2.6 | 9.5 | 5.8 | 6.3 | 6.9 | 9.1 |
| MIC50 | 8 | 8 | 8 | 8 | 8 | 8 | 2 | 2 | 2 | 2 | 2 | 2 |
| MIC90 | 16 | 16 | 16 | 16 | 16 | 16 | 4 | 128 | 128 | 128 | 128 | 128 |
| MIC range | 4 - 16 | 2 - 16 | 4 - 16 | 2 - 16 | 2 - 16 | 2 - 16 | 1 - 128 | 1 - 128 | 1 - 128 | 1 - 128 | 1 - 128 | 1 - 128 |
1GM, geometric mean; MIC50, MIC values that inhibited 50% of the isolates; MIC90, MIC values that inhibited 90% of the isolates.