Table 7.
Diagnostic test characteristics of screening methods for detection of carbapenem-resistant Enterobacterales.
| Test | Diagnostic characteristics1 | J2 | K3 | PCR +/- |
Test +/- |
||
|---|---|---|---|---|---|---|---|
| Se (95% CI) | Sp (95% CI) | Accuracy | |||||
| Carba NP | 67.7 (54.7 – 79.1) | 50.0 (6.8 – 79.1) | 66.7 | 0.18 | 0.06 | 62/4 | 44/22 |
| CARBA 5 | |||||||
| KPC | 100 (63.1 – 100) | 91.7 (61.5 – 99.8) | 95.0 | 0.92 | 0.90 | 8/12 | 9/11 |
| OXA | 92.9 (66.1 – 99.8) | 100 (54.1 – 100) | 95.0 | 0.93 | 0.89 | 14/6 | 13/7 |
| VIM | 83.3 (35.9 – 99.6) | 85.7 (57.2 – 98.2) | 85.0 | 69 | 0.66 | 6/14 | 7/13 |
| NDM | 100 (47.8 – 100) | 100 (78.2 – 100) | 100 | 100 | 1.0 | 5/15 | 5/15 |
| IMP | 77.8 (40.0 – 97.2) | 100 (71.5 - 100) | 90 | 77.8 | 0.79 | 9/11 | 7/13 |
1Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value.
2J: Youden index.
3K: Cohen’s kappa.