Table 1.
Model input parameters.
| Cohort Characteristics | ||
|---|---|---|
| Parameter | Value | Source |
| Mean age (SD) | 55.0 (16.0) | Current Population Survey 2021 [15] |
| Sex, % female | 47% | Current Population Survey 2021 |
| Race, % non-white | 13% | US Census 2018 [43] |
| Mean knee pain at baseline, WOMAC 0–100 (SD) |
45.4 (23.7) | Montana data [9] |
| Mean BMI (SD): active subjects | 29.1 (7.2) | NHANES 2003–2006 [44] |
| Mean BMI (SD): inactive/insufficient subjects | 28.9 (6.3) | NHANES 2003–2006 |
| PA prevalence at baseline Inactive Insufficiently active Active |
20% 42% 38% |
Osteoarthritis Initiative [16,17] |
| Walk With Ease Efficacy | |||
|---|---|---|---|
| Baseline PA Group | PA Group at 6 weeks | % at 6 weeks | Probability of return to background PA at 6 months |
| 1 (inactive) | 1 | 5% | – |
| 2 | 49% | 82% | |
| 3 | 46% | 84% | |
| 2 (insufficiently active) | 1 or 2 | 34% | – |
| 3 | 66% | 88% | |
| 3 (active) | 1 or 2 | 13% | – |
| 3 | 87% | 80% | |
| Treatment Costs (2020 USD) | ||||
|---|---|---|---|---|
| Treatment Regimen | Start-up cost (USD) |
Per-month cost (USD) | Office visit cost (USD) | Office visits per year |
| NSAIDs, PT, devices |
150 | 50 | 125 | 1 |
| Corticosteroid Injections | 0 | 38 | 122 | 1 |
| Tramadol | 0 | 39 | 125 | 2 |
| Oxycodone | 0 | 48 | 125 | 6 |
| TKR | 20,120 | 0 | 119 | 0–1 |
| Walk With Ease | 28 | 16 | – | 0 |