Table 1.
Baseline Patient Characteristics
| Derivation N = 442 |
Validation N = 590 |
|
|---|---|---|
| Mean age (SD), y | 73 (12) | 69 (13) |
| Female, n (%) | 196 (44) | 220 (37) |
| Race, n (%) | ||
| White | 427 (97) | 517 (88) |
| Black | 2 (0.45) | 2 (0.34) |
| Indigenous | 6 (1.4) | 38 (6.4) |
| Asian | 4 (0.90) | 17 (2.9) |
| Other | 3 (0.68) | 5 (0.85) |
| Unknown | 0 (0) | 11 (1.9) |
| Median urine albumin: creatinine (Q1, Q3), mg/mmol | 30 (5, 120) | 94 (19, 232) |
| <3, n (%) | 81 (18) | 10 (1.7) |
| 3-30, n (%) | 141 (32) | 120 (20) |
| >30, n (%) | 220 (50) | 460 (78) |
| Median eGFR CKD-EPIa (Q1, Q3), mL/min/1.73 m2 | 20 (15, 25) | 19 (12, 24) |
| CKD etiology | ||
| Diabetic nephropathy, n (%) | 204 (46) | 274 (46) |
| Hypertensive nephrosclerosis, n (%) | 120 (27) | 90 (15) |
| Glomerulonephritis, n (%) | 18 (4) | 43 (7) |
| Polycystic kidney disease, n (%) | 12 (3) | 16 (3) |
| Other, n (%) | 88 (20) | 167 (28) |
| Comorbid conditions | ||
| Diabetes mellitus, n (%) | 248 (56) | 373 (63) |
| Hypertension, n (%) | N/A | 405 (69) |
| Median KFRE-2 score (Q1, Q3) | 15 (5, 35) | 29 (19, 59) |
Abbreviations: CKD, chronic kidney disease; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; eGFR, estimated glomerular filtration rate; KFRE, Kidney Failure Risk Equation; N/A, not available; Q, quartile; SD, standard deviation.
a
2009 CKD-EPI eGFR equation.