Table 2.

HRs with 95% CIs for the association between change in cardiorespiratory fitness and prostate cancer incidence and mortality

Incidence	Model 1		Model 2		Model 3		Model 4		N	Cases
	HR	95% CI	HR	95% CI	HR	95% CI	HR	95% CI
% change in VO2max (L/min)	0.97***	0.96 to 0.98	0.98**	0.97 to 0.99	0.98**	0.97 to 0.99	0.98**	0.96 to 0.99	57 652	592
Change in VO2max (L/min)	0.29***	0.24 to 0.51	0.45**	0.26 to 0.77	0.44**	0.25 to 0.77	0.46**	0.27 to 0.80	57 652	592
Mortality
% change in VO2max (L/min)	0.98	0.94 to 1.03	0.99	0.95 to 1.02	0.99	0.95 to 1.02	0.98	0.94 to 1.02	57 652	46
Change in VO2max (L/min)	0.48	0.08 to 2.86	0.55	0.12 to 2.53	0.52	0.11 to 2.37	0.38	0.07 to 2.11	57 652	46

Model 1: adjusted for baseline fitness. Model 2: adjusted for baseline fitness, age, education and year of last test. Model 3: adjusted for baseline fitness, age, education, year of last test and body mass index. Model 4: adjusted for baseline fitness, age, education, year of last test, body mass index and smoking.

*p<0.05, **p<0.01, ***p<0.001.

VO_2max, estimated maximal oxygen consumption.