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. 2024 Mar 27;12(3):e008585. doi: 10.1136/jitc-2023-008585

Table 2.

Adverse events reported in clinical study (n=12)

Event SNK01 with GC (n=6) SNK01 with C/GC (n=6)
All grade AEs ≥3 grade AEs All grade AEs ≥3 grade AEs
All AEs 6 (100) 3 (50.0) 6 (100) 2 (33.3)
AEs occurring in ≥2 patients
 Neutropenia 5 (83.3) 3 (50.0) 4 (66.7) 2 (33.3)
 Anemia 3 (50.0) 1 (16.7) 2 (33.3) 0 (0.0)
 Fever 3 (50.0) 0 (0.0) 1 (16.7) 0 (0.0)
 Skin rash 2 (33.3) 0 (0.0) 6 (100) 0 (0.0)
 Diarrhea 2 (33.3) 0 (0.0) 1 (16.7) 0 (0.0)
 Thrombocytopenia 2 (33.3) 0 (0.0) 0 (0.0) 0 (0.0)
 Alopecia 2 (33.3) 0 (0.0) 0 (0.0) 0 (0.0)
 Constipation 1 (16.7) 0 (0.0) 1 (16.7) 0 (0.0)
 Anorexia 1 (16.7) 0 (0.0) 1 (16.7) 0 (0.0)
 Paronychia 0 (0.0) 0 (0.0) 5 (83.3) 0 (0.0)
 Hypomagnesemia 0 (0.0) 0 (0.0) 2 (33.3) 0 (0.0)
SNK01-related AEs* 2 (33.3) 0 (0.0) 1 (16.7) 0 (0.0)

Data are presented as number (percentage).

*All the SNK01-related AEs were fever.

AE, adverse event; C/GC, cetuximab/GC; GC, gemcitabine/carboplatin.