Table 2.
Event | SNK01 with GC (n=6) | SNK01 with C/GC (n=6) | ||
All grade AEs | ≥3 grade AEs | All grade AEs | ≥3 grade AEs | |
All AEs | 6 (100) | 3 (50.0) | 6 (100) | 2 (33.3) |
AEs occurring in ≥2 patients | ||||
Neutropenia | 5 (83.3) | 3 (50.0) | 4 (66.7) | 2 (33.3) |
Anemia | 3 (50.0) | 1 (16.7) | 2 (33.3) | 0 (0.0) |
Fever | 3 (50.0) | 0 (0.0) | 1 (16.7) | 0 (0.0) |
Skin rash | 2 (33.3) | 0 (0.0) | 6 (100) | 0 (0.0) |
Diarrhea | 2 (33.3) | 0 (0.0) | 1 (16.7) | 0 (0.0) |
Thrombocytopenia | 2 (33.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Alopecia | 2 (33.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Constipation | 1 (16.7) | 0 (0.0) | 1 (16.7) | 0 (0.0) |
Anorexia | 1 (16.7) | 0 (0.0) | 1 (16.7) | 0 (0.0) |
Paronychia | 0 (0.0) | 0 (0.0) | 5 (83.3) | 0 (0.0) |
Hypomagnesemia | 0 (0.0) | 0 (0.0) | 2 (33.3) | 0 (0.0) |
SNK01-related AEs* | 2 (33.3) | 0 (0.0) | 1 (16.7) | 0 (0.0) |
Data are presented as number (percentage).
*All the SNK01-related AEs were fever.
AE, adverse event; C/GC, cetuximab/GC; GC, gemcitabine/carboplatin.