Figure 2.

The Prevotellaceae community structure in MSM and non-MSM

(A) Richness and Shannon diversity of Prevotellaceae species members in MSM and non-MSM (adjusted by fixed-effect linear models,³¹ richness p_adj = 1.63e−4, Shannon diversity p_adj = 2.69e−6).

(B) PCoA based on log2-transformed abundances of Prevotellaceae members of MSM and non-MSM (PERMANOVA, R2 = 0.034 and p_adj< 0.001). Marginal density plots show distributions of samples along each axis.

(C) Log2-transformed abundances of Prevotellaceae members with a minimum abundance of 0.1 at 90^th percentile in all subjects. S. copri complex clades are highlighted in red, and uSGBs are denoted in blue. Asterisk signs indicate species differentially enriched in MSM relative to non-MSM.

(D) Percentage of individuals harboring multiple S. copri complex clades (p = 0.001; Wilcoxon rank-sum test). Only samples carrying Prevotellaceae members were considered (MSM n = 84, non-MSM n = 24).

See also Figure S2 and Table S2.