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. 2024 Mar 13;67(6):4870–4888. doi: 10.1021/acs.jmedchem.3c02454

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© 2024 The Authors. Published by American Chemical Society

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Evaluation of the cellular accumulation via real-time live confocal microscopy. Top row: Hormone-dependent MCF-7 cells incubated with (A1) DMF; (A2) GW7604-Pent; (A3) GW7604-Pent-PtCl₃ for 24 h; (A4) GW7604-Pent-PtCl₃ for 48 h. Bottom row: Hormone-independent SKBr3 cells incubated with (B1) DMF; (B2) GW7604-Pent; (B3) GW7604-Pent-PtCl₃ for 24 h; (B4) GW7604-Pent-PtCl₃ for 48 h. Compound concentration: 20 μM.