Scheme 1. Synthesis of the GW7604-Alk-PtCl3 Complexes (Alk = Prop (n = 1), But (n = 2), Pent (n = 3), Hex (n = 4), Reagents and Conditions: (i) TBDMSCl, DMF, Imidazole, rt, 24 h; (ii) DMAP, Alkenol (n = 1–4), EDC, DCM, 0 °C to rt, 17 h, 55–100%; (iii) TBAF, THF, 0 °C to rt, 3 h, 55–93%; (iv) K[PtCl3(C2H4)], EtOH, 48–50 °C, 3 h, 33–56%.
