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. 2024 Feb 29;5(3):101445. doi: 10.1016/j.xcrm.2024.101445

Figure 2.

Figure 2

Sera from CF501/RBD-Fc-immunized macaques showed high levels of RBD-binding IgG endpoint titers against XBB.1.5, XBB.1.16, CH.1.1, EG.5, and BA.2.86

(A) Vaccination and sample collection timeline in rhesus macaques (n = 3).

(B–F) The endpoint titers of RBD-specific antibodies against XBB.1.5 (B), XBB.1.16 (C), CH.1.1 (D), EG.5 (E), and BA.2.86 (F) in sera from macaques immunized with CF501/RBD-Fc or Alum/RBD-Fc from days 28 to 191 post-first immunization. Data are shown as mean ± SEM. The experiments were repeated a minimum of two times. Two-way ANOVA was used to compare endpoint titers between CF501/RBD-Fc and Alum/RBD-Fc. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001.