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. 2024 Mar 18;15:1337520. doi: 10.3389/fimmu.2024.1337520

Table 1.

Results of ordered logistic regression analysis.

Variables N = 1353 Wuhan XBB 1.5
Univariable analysis Multivariable analysis Univariable analysis Multivariable analysis
OR (95% CI) p-value aOR (95% CI) p value OR (95% CI) p-value aOR (95% CI) p value
Age 50 [39-63]
- 40 years old 376(27.8) 1(ref) 1(ref) 1(ref) 1(ref)
41 - 60 years old 585(43.2) 1.10 (0.87—1.38) 0.42 1.01 (0.77—1.32) 0.95 0.81 (0.65—1.02) 0.07 0.86 (0.66—1.12) 0.25
61- years old 392(29.0) 1.01 (0.79—1.30) 0.94 1.05 (0.77—1.44) 0.75 0.61 (0.47—0.78) <0.001 0.70 (0.27—1.76) 0.44
Smoking 210(15.5) 0.88 (0.68—1.15) 0.35 0.90 (0.68—1.18) 0.44 1.01 (0.78—1.32) 0.93 0.93 (0.71—1.22) 0.60
Drinking Habit 480(35.5) 0.84 (0.68—1.04) 0.10 0.86 (0.7—1.07) 0.18 0.85 (0.69—1.04) 0.12 0.89 (0.72—1.11) 0.31
Comorbidity 719(53.1) 0.92 (0.76—1.11) 0.37 1.00 (0.8—1.25) 0.99 0.74 (0.61—0.89) <0.001 0.76 (0.61—0.96) 0.02
Days from the last vaccination 143 [118-168]
- 3 months 82(6.1) 1(ref) 1(ref) 1(ref) 1(ref)
3 - 6 months 1079(79.7) 0.37 (0.26—0.54) <0.001 0.43 (0.28—0.67) <0.001 0.53 (0.36—0.77) <0.001 0.66 (0.43—1.01) 0.06
6- months 183(13.5) 0.40 (0.26—0.63) <0.001 0.38 (0.15—0.97) 0.04 0.59 (0.38—0.92) 0.02 0.70 (0.27—1.76) 0.44
Type of the last vaccination *1missing value
Pfizer monovalent 98(7.2) 1(ref) 1(ref) 1(ref) 1(ref)
Pfizer BA.1/BA.2 98(7.2) 2.30 (1.40—3.76) <0.001 1.52 (0.60—3.90) 0.38 2.88 (1.76—4.71) <0.001 3.41 (1.33—8.73) 0.01
Pfizer BA.4/BA.5 933(69.0) 1.03 (0.71—1.49) 0.86 0.85 (0.34—2.12) 0.73 1.12 (0.78—1.62) 0.54 1.20 (0.48—2.99) 0.70
Moderna monovalent 82(6.1) 1.33 (0.79—2.22) 0.28 1.06 (0.59—1.93) 0.84 1.80 (1.08—3.01) 0.03 1.75 (0.97—3.16) 0.06
Moderna BA.1/BA.2 127(9.4) 2.40 (1.50—3.83) <0.001 2.05 (0.79—5.38) 0.14 3.89 (2.44—6.20) <0.001 4.31 (1.65—11.31) <0.001
ModernaBA.4/BA.5 14(1.0) 0.87 (0.33—2.33) 0.79 0.78 (0.21—2.96) 0.72 1.73 (0.65—4.60) 0.27 1.99 (0.52—7.51) 0.31
Past Infection IgG(N) ≧10.0 AU/mL 253(18.7) 3.15 (2.46—4.02) <0.001 3.36 (2.53—4.46) <0.001 2.00 (1.57—2.54) <0.001 1.77 (1.34—2.33) <0.001

Median [interquartile] or number (percentage) are shown for continuous or categorical variables. 95% CI, 95% confidence interval; aOR, adjusted odds ratio; OR, odds ratio.