Table 1.
Variables | N = 1353 | Wuhan | XBB 1.5 | ||||||
---|---|---|---|---|---|---|---|---|---|
Univariable analysis | Multivariable analysis | Univariable analysis | Multivariable analysis | ||||||
OR (95% CI) | p-value | aOR (95% CI) | p value | OR (95% CI) | p-value | aOR (95% CI) | p value | ||
Age | 50 [39-63] | ||||||||
- 40 years old | 376(27.8) | 1(ref) | – | 1(ref) | – | 1(ref) | – | 1(ref) | – |
41 - 60 years old | 585(43.2) | 1.10 (0.87—1.38) | 0.42 | 1.01 (0.77—1.32) | 0.95 | 0.81 (0.65—1.02) | 0.07 | 0.86 (0.66—1.12) | 0.25 |
61- years old | 392(29.0) | 1.01 (0.79—1.30) | 0.94 | 1.05 (0.77—1.44) | 0.75 | 0.61 (0.47—0.78) | <0.001 | 0.70 (0.27—1.76) | 0.44 |
Smoking | 210(15.5) | 0.88 (0.68—1.15) | 0.35 | 0.90 (0.68—1.18) | 0.44 | 1.01 (0.78—1.32) | 0.93 | 0.93 (0.71—1.22) | 0.60 |
Drinking Habit | 480(35.5) | 0.84 (0.68—1.04) | 0.10 | 0.86 (0.7—1.07) | 0.18 | 0.85 (0.69—1.04) | 0.12 | 0.89 (0.72—1.11) | 0.31 |
Comorbidity | 719(53.1) | 0.92 (0.76—1.11) | 0.37 | 1.00 (0.8—1.25) | 0.99 | 0.74 (0.61—0.89) | <0.001 | 0.76 (0.61—0.96) | 0.02 |
Days from the last vaccination | 143 [118-168] | ||||||||
- 3 months | 82(6.1) | 1(ref) | – | 1(ref) | – | 1(ref) | – | 1(ref) | – |
3 - 6 months | 1079(79.7) | 0.37 (0.26—0.54) | <0.001 | 0.43 (0.28—0.67) | <0.001 | 0.53 (0.36—0.77) | <0.001 | 0.66 (0.43—1.01) | 0.06 |
6- months | 183(13.5) | 0.40 (0.26—0.63) | <0.001 | 0.38 (0.15—0.97) | 0.04 | 0.59 (0.38—0.92) | 0.02 | 0.70 (0.27—1.76) | 0.44 |
Type of the last vaccination | *1missing value | ||||||||
Pfizer monovalent | 98(7.2) | 1(ref) | – | 1(ref) | – | 1(ref) | – | 1(ref) | – |
Pfizer BA.1/BA.2 | 98(7.2) | 2.30 (1.40—3.76) | <0.001 | 1.52 (0.60—3.90) | 0.38 | 2.88 (1.76—4.71) | <0.001 | 3.41 (1.33—8.73) | 0.01 |
Pfizer BA.4/BA.5 | 933(69.0) | 1.03 (0.71—1.49) | 0.86 | 0.85 (0.34—2.12) | 0.73 | 1.12 (0.78—1.62) | 0.54 | 1.20 (0.48—2.99) | 0.70 |
Moderna monovalent | 82(6.1) | 1.33 (0.79—2.22) | 0.28 | 1.06 (0.59—1.93) | 0.84 | 1.80 (1.08—3.01) | 0.03 | 1.75 (0.97—3.16) | 0.06 |
Moderna BA.1/BA.2 | 127(9.4) | 2.40 (1.50—3.83) | <0.001 | 2.05 (0.79—5.38) | 0.14 | 3.89 (2.44—6.20) | <0.001 | 4.31 (1.65—11.31) | <0.001 |
ModernaBA.4/BA.5 | 14(1.0) | 0.87 (0.33—2.33) | 0.79 | 0.78 (0.21—2.96) | 0.72 | 1.73 (0.65—4.60) | 0.27 | 1.99 (0.52—7.51) | 0.31 |
Past Infection IgG(N) ≧10.0 AU/mL | 253(18.7) | 3.15 (2.46—4.02) | <0.001 | 3.36 (2.53—4.46) | <0.001 | 2.00 (1.57—2.54) | <0.001 | 1.77 (1.34—2.33) | <0.001 |
Median [interquartile] or number (percentage) are shown for continuous or categorical variables. 95% CI, 95% confidence interval; aOR, adjusted odds ratio; OR, odds ratio.