TABLE 2.
Adverse events (all grades and grade ≥3).
| Adverse event | n of pts (%)—Overall population | n of pts (%)—Pts aged ≥75 (n = 36) | ||
|---|---|---|---|---|
| All grades | Grade ≥3 | All grades | Grade ≥3 | |
| Hematological | ||||
| Anemia | 41 (38.7) | 5 (4.7) | 12 (33.3) | 1 (2.8) |
| Thrombocytopenia | 39 (36.8) | 18 (16) | 14 (38.9) | 8 (22.2) |
| Neutropenia | 37 (34.9) | 13 (12.3) | 14 (38.9) | 4 (11.1) |
| Non‐hematological | ||||
| Infection | 23 (21.7) | 10 (9.4) | 5 (13.9) | 2 (5.5) |
| GI (diarrhea) | 31 (29.2) | 6 (5.7) | 10 (27.8) | 3 (8.3) |
| GI (LFTs abnormalities) | 7 (6.6) | 3 (2.8) | 1 (2.8) | 0 |
| VTE | 4 (3.8) | 3 (2.8) | 0 | 0 |
| Skin rash | 15 (14.1) | 2 (1.9) | 9 (25) | 2 (5.5) |
| Peripheral neuropathy | 28 (26.4) | 0 | 6 (16.7) | 0 |
| Other | 17 (16.0) | 2 (1.9) | 3 (8.3) | 0 |
Abbreviations: GI, gastrointestinal; LFTs, liver function tests; n, number; VTE, venous thromboembolism.