TABLE 1.
Cellular host range of HIV-2 strains ARM and SARa
| Cells | Host range/CPE
|
|
|---|---|---|
| HIV-2 ARM | HIV-2 SAR | |
| Peripheral blood cells | ||
| PBMC | ++/+ | ++/+ |
| MDM | −/− | −/− |
| PBL | ++/+ | ++/+ |
| T-cell lines | ||
| CEM | −/− | −/− |
| HUT78 | −/− | −/− |
| Jurkat-tat III | ++/− | +++/+ |
| SupT1 | −/− | ++/− |
| U937 monocytes | −/− | −/− |
a
All results are means of three different experiments. Host range was determined by virus replication as assessed by RT activity in culture supernatants. Results were considered positive when values were at least five times the background level. +++, >2 × 106 cpm/ml; ++, 1 × 106 to 2 × 106 cpm/ml; −, <1 × 104 cpm/ml. Cytopathic effect (CPE) scoring was based on the presence (+) or absence (−) of syncytium formation.