Table 6.

Proportion of Medications Appearing in Cluster 7 by Day and Fluid Overload Status

Proportion of Medications Matching Cluster 7, median (IQR)	Fluid Overload Group	Non-Fluid Overload Group
Hours 0–24 of ICU admission	52.4 (33.9–70.4)	33.3 (14.3–51.2)
Hours 25–48 of ICU admission	50 (22.2–65.4)	18.8 (5.6–40.7)
Hours 49–72 of ICU admission	32.4 (11.8–50)	7.7 (0–22.5)
Hours 0–72 of ICU admission	46.3 (30.4,60.7)	25.2 (11.8–40)

Proportions are calculated on a patient-specific level; the percentage is reported is the median proportion of medications matching Cluster 7 using individual patient data rather than aggregate data. For example, of the medications received in the first 24 hours of ICU stay, 52.4% of those medications were also present in Cluster 7 for the median patient in the fluid overload group, compared to 33.3% of medications in the non-fluid overload group.