Figure 4.
Virulence genes required by K. aerogenes SK431 for colonization in differential mucosal sites. The relative tn abundance (log10TnPKM, left) and signal-to-noise (input to output) ratio (SNR, right) of virulence gene mutants of indicated groups are depicted in heatmaps. The gene IDs of each operon are listed. T6SS1 and T6SS2 represent two core operons of T6SS. [Left; TnPKM]: higher gene abundance is indicated in red, while lower abundance is shown in blue. [Right; SNR]: genes required in input (IN) condition are indicated in yellow. Genes required in output conditions are shown in red. *, genes with significant differences (fold differences > 10, |SNR| > 0.5, FDR < 0.05, p < 0.05).