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. 2024 Mar 28;18:953–965. doi: 10.2147/DDDT.S449066

Table 3.

Comparison of Motor Nerve Amplitude Before and After Nusinersen Treatment in SMA Patients

Nerve Location Side Amplitude(mV)Median (P25, P75) Kruskal–Wallis Test Statistic H-value p
T0 (n=42) T6 (n=42) T14 (n=21)
Median Nerve Distal Right 6.115(3.9,9.2) 6.075(4.6,8.3) 5.710(4.3,7.7) 0.148 0.928
Left 4.570(3.1,8.4) 5.740(3.3,8.5) 6.420(3.7,10.1) 1.693 0.429
Proximal Right 5.080(3.0,7.8) 5.120(3.7,7.6) 4.800(3.4,6.1) 0.251 0.882
Left 4.070(2.3,6.6) 4.950(2.2,6.9) 4.700(3.3,7.5) 1.505 0.471
Ulnar nerve Distal Right 2.065(1.2,4.9) 2.495(0.9,4.3) 2.040(1.5,4.3) 0.014 0.993
Left 1.985(1.0,4.0) 2.160(1.1,4.9) 2.230(1.5,4.2) 0.532 0.767
Proximal Right 2.360(1.0,4.8) 2.355(1.3,4.5) 1.930(1.0,3.6) 0.526 0.769
Left 1.955(0.9,4.7) 2.240(1.1,4.8) 2.180(1.2,3.6) 0.154 0.926
Axillary nerve Right 4.480(1.6,7.0) 4.420(2.0,8.3) 3.590(2.5,4.5) 1.329 0.514
Left 3.235(1.7,6.8) 3.170(1.9,8.4) 3.270(2.0,4.4) 0.535 0.765
Common peroneal nerve Proximal Right 2.450(0.9,4.4) 3.195(1.1,4.9) 2.200(0.7,3.4) 1.736 0.42
Left 2.665(1.7,4.5) 2.620(1.3,4.3) 1.840(0.9,3.7) 2.558 0.278
Distal Right 2.375(1.0,4.5) 3.825(1.4,5.3) 1.770(0.8,3.6) 2.028 0.363
Left 2.820(1.0,5.1) 2.695(1.1,4.4) 1.820(0.9,2.7) 2.417 0.299
Tibial nerve Proximal Right 1.630(0.9,4.2) 1.995(0.8,4.2) 1.790(0.5,4.2) 0.158 0.924
Left 1.565(0.5,5.2) 1.770(0.7,4.4) 1.520(0.4,2.7) 0.865 0.649
Distal Right 2.705(1.3,5.6) 2.870(1.1,5.6) 2.030(1.1,4.4) 0.52 0.771
Left 2.200(0.8,6.4) 2.285(0.9,5.6) 2.170(1.1,4.9) 0.045 0.978
Femoral nerve Right 0.415(0.2,1.0) 0.685(0.2,1.7) 0.970(0.2,2.0) 1.724 0.422
Left 0.495(0.1,0.9) 0.675(0.2,1.2) 0.590(0.3,1.5) 1.746 0.418