Skip to main content
. 2024 Mar 2;16(3):e55396. doi: 10.7759/cureus.55396

Table 12. Percentage of live and dead cells from different cell lines treated with I. coccinea leaf ethyl acetate extract.

SD: standard deviation; IC50: half-maximal inhibitory concentration; SEM: standard error of mean; HaCaT cell line: keratinocyte cell line

Values are means of triplicate experiments

Cell line used HaCaT cell line Human dermal fibroblasts A375 cell lines (malignant melanoma cell lines)
Concentration of extract (µg/mL) % cell death mean SD SEM % live cells % cell death SD SEM % live cells % cell death SD SEM % live cells
100 48.98 1.39 0.80 51.02 63.98 0.56 0.32 36.02 86.30 7.95 4.59 13.70
50 44.97 0.98 0.56 55.03 49.77 2.17 1.25 50.23 84.24 1.27 0.73 15.76
25 39.18 1.74 1.00 60.82 41.19 0.66 0.38 58.81 66.34 7.29 4.21 33.66
12.5 30.48 1.42 0.82 69.52 32.58 0.58 0.34 67.42 59.98 5.94 3.43 40.02
6.25 21.84 1.27 0.74 78.16 29.97 0.56 0.32 70.03 53.55 4.69 2.71 46.45
3.125 21.22 1.01 0.58 78.78 27.63 0.65 0.38 72.37 37.54 2.40 1.39 62.46
1.5 12.38 1.58 0.91 87.62 15.42 4.12 2.38 84.58 24.67 3.57 2.06 75.33
Control       100       100.00       100
IC50 98.52 µg/mL IC50 58.52 µg/mL IC50 7.96 µg/mL