. 2024 Feb;34(2):243–255. doi: 10.1101/gr.278133.123

Table 1.

Features of chromatin environments of MPRA library sequences

Group	Histone marks		Typical distance to TSS	CRX-dependent accessibility	Timing and specificity of accessibility	No. of CREs in MPRA library
Group	H3K4me3	H3K27ac	Typical distance to TSS	CRX-dependent accessibility	Timing and specificity of accessibility	No. of CREs in MPRA library
A	+	+	0–5 kb	Independent	Open in other cell types, always accessible	249
A	+	+	0–5 kb	Dependent	Retina-specific, late accessibility	632
C	−	+	5–500 kb	Independent	Retina-specific, early accessibility	311
C	−	+	5–500 kb	Dependent	Retina-specific, late accessibility	366
D	−	−	5–500 kb	Independent	Retina-specific, intermediate accessibility	76
D	−	−	5–500 kb	Dependent	Retina-specific, early accessibility	89