TABLE 2.

Coefficients of linear mixed‐effects models' interaction (weeks:rTMS[active]) showing the effect of rTMS on NODDI metrics from frontostriatal circuits' white matter (WM) tracts.

WM‐ROI	Estimate	Std. error	df	Effect size	p value	FDR a
Neurite density (ICVF)
DLPFC2rvmPFC	0.034	0.012	42.36	−0.112	0.009 a	0.065
vmPFC2DLPFC	0.038	0.015	42.31	−0.278	0.013 a	0.065
Orientation dispersion (OD)
DLPFC2Caud	0.009	0.004	40.65	−0.087	0.021 a	0.105
DLPFC2Thal	0.006	0.003	40.68	−0.489	0.045 a	0.150
vmPFC2DLPFC	0.027	0.010	41.91	0.024	0.012 a	0.105
${\mathit{\text{NODDI}}}_{{\mathit{ROI}}_i}={\beta }_0+{\beta }_1·\mathit{\text{weeks}}+{\beta }_2·\mathit{\text{rTMS}}\left[\mathit{\text{active}}\right]+{\beta }_3·\mathit{age}+{\beta }_4·\mathit{\text{educationyears}}+{\beta }_5·\mathit{\text{weeks}}·\mathit{\text{rTMS}}\left[\mathit{\text{active}}\right]$

Abbreviations: DLPFC2Caud, WM connecting left rostral middle frontal cortex (RMFC) and left caudate nucleus; DLPFC2rvmPFC, WM connecting left RMFC and right medial orbitofrontal cortex (MOC); DLPFC2Thal, WM connecting left RMFC and left thalamus; vmPFC2DLPFC, WM connecting left MOC and left RMFC; WM‐ROI, white matter region of interest; Std., standard; df; degrees of freedom; NODDI, neurite orientation dispersion and density imaging model; rTMS, repetitive transcranial magnetic stimulation, ICVF, intra‐cellular volume fraction; ISOVF, isotropic volume fraction; OD, orientation dispersion.

^a False discovery rate (FDR) adjustment was implemented with p values of their own metric, full values are found in Tables S1–S3.