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Trajectories of brain MRI changes over 6 years of follow‐up by presence of mild/complex multimorbidity. Linear mixed models were adjusted for age, sex, education and APOE genotype. All volumes are adjusted for total intracranial volume and converted into z‐scores. APOE, apolipoprotein E; MRI: magnetic resonance imaging; TBTV: total brain tissue volume; WMH: white matter hyperintensities.
