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. 2024 Apr 1;19(4):e0296945. doi: 10.1371/journal.pone.0296945

Table 3. Estimated short- and long-term cumulative changes in CRC incidence and CRC mortality attributable to screening, diagnosis, and treatment decreases in 2020 and 2021.

All results are vs “no pandemic” scenario (see Table 1). Numbers in brackets are relative changes. Includes short-term decreases to incidence due to reductions in diagnoses, and long-term increases due to CRC which were not removed at screening at a precancerous stage.

2020–2021 2020–2025 2020–2030 2020–2050
Australia Changes in CRC incidence vs no pandemic -1,672 (-4.7%) -630 (-.6%) 234 (.1%) 1,065 (.1%)
Changes in CRC mortality vs no pandemic Screening-related -9 40 123 396
Diagnoses/treatment related 100 764 1,063 1,068
Total (no mitigation) 91 (1.1%) 805 (3.1%) 1,186 (2.4%) 1,464 (0.9%)
Total (5% mitigation) 91 (1.1%) 631 (2.4%) 842 (1.7%) 1,114 (0.7%)
Canada Changes in CRC incidence vs no pandemic -1,398 (-3.1%) -195 (-.2%) 255 (.1%) 443 (.%)
Changes in CRC mortality vs no pandemic Screening-related -16 194 525 805
Diagnoses/treatment related 334 1,079 1,296 1,070
Total (no mitigation) 318 (2.0%) 1,272 (2.6%) 1,820 (1.9%) 1,875 (.6%)
Total (5% mitigation) 306 (1.9%) 629 (1.3%) 1,031 (1.1%) 1,053 (.3%)