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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Cytotherapy. 2023 Jun 16;25(9):977–985. doi: 10.1016/j.jcyt.2023.05.012

Figure 2. Linearity and maximally selected log-rank statistics analyses on the correlation between CD4 immune reconstitution and non-relapse mortality.

Figure 2.

(a) Martingale residual plot demonstrating excess risk of non-relapse mortality by highest achieved absolute CD4 count in the first 100 days after allo-HCT. The nonlinear trajectory of the curve indicates there is no linear correlation between CD4 cell count and non-relapse mortality, (b) distribution of the CD4 values, (c) maximally selected log-rank statistics determining an absolute CD4 count of 57 as the cut off for NRM, (d) cumulative incidence curves of NRM comparing patients who achieved a maximum CD4 count > 57 (dotted line) and those who did not (solid line), confirming a significant difference between the two groups. P value depicts significance of CD4 IR > 57 as predictor in univariable competing risk analyses by the Fine-Gray method.