Table 2. Age, sex, and anatomical-related differences of personal medical, surgical and family history of cancer.
| Characteristic | N | Sex | Anatomic site | Age category | Overall N = 255 a |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Female N = 110 a |
Male N = 145 a |
p-value b | Colon N = 158 a |
Rectum N = 97 a |
p-value b | < 50 N = 56 a |
≥ 50 N = 199 a |
p-value b | |||
| Personal medical history | 255 | 56 (51%) | 63 (43%) | 0.200 | 79 (50%) | 40 (41%) | 0.200 | 8 (14%) | 111 (56%) | < 0.001* | 119 (47%) |
| Hypertension | 253 | 27 (25%) | 22 (15%) | 0.058 | 33 (21%) | 16 (17%) | 0.400 | 1 (1.8%) | 48 (24%) | < 0.001* | 49 (19%) |
| Diabetes | 253 | 14 (13%) | 22 (15%) | 0.600 | 27 (17%) | 9 (9.5%) | 0.093 | 1 (1.8%) | 35 (18%) | 0.003* | 36 (14%) |
| Stroke | 253 | 1 (0.9%) | 3 (2.1%) | 0.600 | 3 (1.9%) | 1 (1.1%) | > 0.900 | 0 (0%) | 4 (2.0%) | 0.600 | 4 (1.6%) |
| Other personal medical history | 252 | 30 (28%) | 32 (22%) | 0.300 | 43 (27%) | 19 (20%) | 0.200 | 4 (7.1%) | 58 (30%) | < 0.001* | 62 (25%) |
| Personal surgical history | 255 | 49 (45%) | 53 (37%) | 0.200 | 71 (45%) | 31 (32%) | 0.040* | 18 (32%) | 84 (42%) | 0.200 | 102 (40%) |
| Appendicectomy | 250 | 7 (6.4%) | 12 (8.5%) | 0.500 | 16 (10.3%) | 3 (3.2%) | 0.041* | 3 (5.4%) | 16 (8.2%) | 0.600 | 19 (7.6%) |
| Cholecystectomy | 250 | 8 (7.3%) | 3 (2.1%) | 0.062 | 9 (5.8%) | 2 (2.1%) | 0.200 | 0 (0%) | 11 (5.7%) | 0.130 | 11 (4.4%) |
| Other personal surgical history | 250 | 37 (34%) | 39 (28%) | 0.300 | 51 (33%) | 25 (27%) | 0.300 | 16 (29%) | 60 (31%) | 0.700 | 76 (30%) |
| Family history of cancer | 230 | 44 (44%) | 46 (36%) | 0.200 | 62 (43%) | 28 (33%) | 0.140 | 17 (33%) | 73 (41%) | 0.300 | 90 (39%) |
| First degree CRC | 232 | 0.800 | 0.700 | 0.700 | |||||||
| One | 9 (8.8%) | 11 (8.5%) | 14 (9.6%) | 6 (7.0%) | 3 (5.8%) | 17 (9.4%) | 20 (8.6%) | ||||
| multiple | 1 (1.0%) | 3 (2.3%) | 3 (2.1%) | 1 (1.2%) | 1 (1.9%) | 3 (1.7%) | 4 (1.7%) | ||||
| No history | 92 (90%) | 116 (89%) | 129 (88%) | 79 (92%) | 48 (92%) | 160 (89%) | 208 (90%) | ||||
| Second degree CRC | 232 | 0.200 | 0.300 | 0.600 | |||||||
| One | 6 (5.8%) | 3 (2.3%) | 8 (5.5%) | 1 (1.1%) | 3 (5.8%) | 6 (3.3%) | 9 (3.9%) | ||||
| Multiple | 3 (2.9%) | 1 (0.8%) | 3 (2.1%) | 1 (1.1%) | 1 (1.9%) | 3 (1.7%) | 4 (1.7%) | ||||
| No history | 94 (91%) | 125 (97%) | 134 (92%) | 85 (98%) | 48 (92%) | 171 (95%) | 219 (94%) | ||||
| First degree NO- CRC | 229 | 0.054 | 0.200 | 0.200 | |||||||
| One | 27 (27%) | 20 (16%) | 33 (23%) | 14 (16%) | 6 (12%) | 41 (23%) | 47 (21%) | ||||
| Multiple | 5 (5.0%) | 3 (2.3%) | 7 (4.9%) | 1 (1.2%) | 2 (3.8%) | 6 (3.4%) | 8 (3.5%) | ||||
| No history | 69 (68%) | 105 (82%) | 104 (72%) | 70 (82%) | 44 (85%) | 130 (73%) | 174 (76%) | ||||
| Second degree non- CRC | 231 | 0.080 | 0.700 | 0.130 | |||||||
| One | 0 (0%) | 6 (4.7%) | 3 (2.1%) | 3 (3.4%) | 3 (5.8%) | 3 (1.7%) | 6 (2.6%) | ||||
| Multiple | 6 (5.9%) | 7 (5.4%) | 9 (6.3%) | 4 (4.6%) | 1 (1.9%) | 12 (6.7%) | 13 (5.6%) | ||||
| No history | 96 (94%) | 116 (90%) | 132 (92%) | 80 (92%) | 48 (92%) | 164 (92%) | 212 (92%) | ||||
*
p-value significant at below 0.050 threshold;
a
n (%);
b
Wilcoxon rank sum test;
Fisher’s exact test; Pearson’s chi-squared test