Table 1 List of drugs that can regulate ferroptosis in AS

Drug	Target	Mechanism	Ref.
DiDang decoction	Upregulate GPX4	Improve mitochondrial function	[154]
Hydroxysafflor yellow A	Regulate SLC7A11 expression	Reduce atherosclerotic plaque formation	[155]
Sulforaphane and EPI-742	Regulate NRF2	Regulate lipid peroxidation	[156]
Vitamin E	Regulate NRF2	Regulate iron homeostasis	[157]
Micheliolide	Regulate NRF2	Regulate ferroptosis in macrophages	[158]
MI-2	Inhibit MALT1	Inhibit ferroptosis of vascular SMCs	[159]
Icariin	Promote autophagy	Inhibit ferroptosis	[160]