Figure 7 .

PLAT inhibits thyroid cancer angiogenesis through VEGFa/VEGFR2

(A) Tube formation ability of HUVECs cultured for 4 h in the TCM from NC, OE and OE+hVEGFA. (B) Wound healing ability of HUVECs after 24 h and 48 h in the TCM from NC and OE. (C) Western blot analysis showed that VEGFA protein expression was downregulated in OE cells. (D) Western blot analysis showed that VEGFR2 protein expression was downregulated in HUVECs in TCM from transfected IHH4 and TPC-1 cells overexpressing PLAT. Magnification: 50×. *P<0.05, **P<0.01.