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. 2023 Oct 26;14(5):1189–1205. doi: 10.1007/s13346-023-01454-0

Table 2.

Effect of permeation enhancers, free or nanoencapsulated, supplementation on the lifespan of C. elegans, expressed as mean, median, and maximum life expectancy. NGM: control, n ≥ 70 worms

Treatment Mean survival (days) Median survival (days) Maximum (days)
NGM 13 16 ± 1 24 ± 2
DS 13 18 ± 3 23 ± 1
DOCU 17 20 ± 1 25 ± 2
DS-NP-P 15 16 ± 2 26 ± 2
DOCU-NP-P 13 15 ± 1 24 ± 2