Table 1.
Baseline characteristics of the study population
| Value | |
|---|---|
| Age (years) | 71 [65–77] |
| Female | 53% |
| BMI (kg/m2) | 27.8 ± 7.8 |
| APACHE | 18.3 ± 8.3 |
| SOFA | 9.2 ± 2.5 |
| CRP (mg/dL) | 24.1 ± 15.2 |
| Sepsis Source | |
| Abdominal | 55% (19) |
| Respiratory | 24% (8) |
| Urinary | 9% (3) |
| Soft tissue | 6% (2) |
| Other | 6% (2) |
| Previous fluid resuscitation (mL) | 1610 [670–2868] |
| NE dose (mcg/kg/min) | 0.19 ± 0.15 |
| Vasopressin use (%) | 17% |
| MAP (mmHg) | 67 [64–70] |
| HR (bpm) | 92 ± 18 |
| CRT (s) | 4 [3.1-6] |
| Lactate (mmol/L) | 3 [2.3–4.3] |
| CVP (mmHg) | 8.6 ± 4.8 |
| Cardiac output (L/min) | 4.9 ± 1.7 |
| Central venous O2saturation (%) | 77 [69–84] |
| Venous-arterial pCO 2 gradient | 4.4 ± 2.5 |
BMI: Body Mass Index; APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: Sequential Organ Failure Assessment; CRP: c-reactive protein; NE: norepinephrine; MAP: mean arterial pressure; HR: heart rate; CRT: capillary refill time; CVP: central venous pressure. Data is presented as mean ± SD or median [interquartile range]