Table 3.

Comparison of different clinical, hemodynamic and perfusion variables at baseline in CRT-responders versus non-responders to the vasopressor test

	Responders	Non-responders	p-value
Number of patients	14	11
Age (years)	76 [66–81]	68 [66–78]	0.3
APACHE	20 ± 9.3	19.6 ± 5.7	0.9
SOFA	9.3 ± 2.4	9.4 ± 2.6	0.34
CRP (mg/dL)	31.1 ± 14.5	20.4 ± 16.3	0.004
CO (L/min)	3.9 ± 1.2	5.5 ± 1.3	0.047
NE dose (mcg/kg/min)	0.13 ± 0.11	0.24 ± 0.13	0.12
CVP (mmHg)	7.4 ± 4.4	11 ± 5.1	0.7
HR (bpm)	86 ± 15	89 ± 16	0.056
CRT (s)	5.0 [3.8–6.5]	3.7 [3–5]	0.49
Lactate (mmol/L)	2.5 [2-3.3]	3.8 [1.6–8.8]	0.1
Central venous O2 saturation (%)	69 [65–84]	82 [74–85]	0.7
Venous-arterial pCO2 gradient (mmHg)	3 [1–4]	3 [3–6]	0.8

APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: Sequential Organ Failure Assessment; APACHE: Acute Physiology and Chronic Health Evaluation; CRP: c-reactive protein; CO: cardiac output; NE: norepinephrine; CVP: central venous pressure; HR: heart rate; CRT: capillary refill time. Data is presented as mean +- SD or median [interquartile range]. Students’ t-test or Mann-Whitney U-test used accordingly