Table 2.
Univariate logistic regression analysis of clinical biological indicators and the disease activity of SLE.
| Parameters | OR (95%CI) | P value |
|---|---|---|
| Sex | 1.785 (0.193–16.468) | 0.609 |
| Age | 1.033 (0.985–1.083) | 0.177 |
| Duration of SLE | 0.996 (0.985–1.007) | 0.497 |
| HCQ daily dose | 1.001 (0.996–1.007) | 0.681 |
| Duration of HCQ treatment | 0.994 (0.981–1.006) | 0.321 |
| Body mass dependent dose | 1.070 (0.832–1.375) | 0.599 |
| Cumulative dose of HCQ | 1.000 (0.998–1.001) | 0.530 |
| HCQ blood concentration | 0.997 (0.993–1.000) | 0.042* |
| GCs dosage | 0.997 (0.889–1.117) | 0.954 |
| Immunosuppressant | 0.466 (0.132–1.640) | 0.234 |
| CRP | 1.110 (0.963–1.278) | 0.149 |
| ESR | 1.024 (0.970–1.080) | 0.394 |
| BUN | 1.046 (0.753–1.452) | 0.791 |
| SCr | 1.008 (0.982–1.034) | 0.544 |
| eGFR | 0.982 (0.956–1.009) | 0.183 |
OR odds ratio, CI confidence interval, HCQ hydroxychloroquine, SLE systemic lupus erythematosus, GCs glucocorticoids, CRP C-reactive protein, ESR erythrocyte, BUN blood urea nitrogen, SCr serum creatinine.
*P < 0.05 was considered statistically significant.