Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Apr 1;15:2813. doi: 10.1038/s41467-024-47048-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — a Permutation test showing CTCF had higher level of binding on strengthened CTCF-related E-P interactions than randomly shuffled set of CTCF peaks. p-value by one-tailed test based on the assumption of normal distribution, p = 0.002. b Pie chart showing the percent of strengthened CTCF-related E-P interactions with enhanced CTCF peaks (left) and the percent of increased expression genes targeted by strengthened CTCF-related E-P interactions with enhanced CTCF peaks (right). p-value by one-tailed chi-square test, p = 0.035. c GSEA of genes targeted by strengthened CTCF-related E-P interactions with enhanced CTCF peaks. d GO analysis of genes targeted by strengthened CTCF-related E-P interactions with enhanced CTCF peaks, p-values by Fisher’s Exact test. e Model of the role of O-GlcNAcylation in CTCF chromatin binding and 3D chromatin structure. f Representative genomic loci showing up-regulated genes targeted by strengthened E-P interaction with enhanced CTCF peaks. Source data are provided as a Source Data file.