Table 1.
Neuronal, immune and epithelial-related GO terms enriched in miR-183C targets in TG sensory neurons.
| GO ID | Terms | P | Genes | Fold enrichment |
|---|---|---|---|---|
| Neuronal related | ||||
| 0010976 | Positive regulation of neuron projection development | 0.0023 | EHD1, RGS2, ANKRD27, ITGA3, STMN2, FYN, CX3CL1 | 5.17 |
| 1902667 | Regulation of axon guidance | 0.0428 | NOVA2, MYCBP2 | 45.59 |
| 0031175 | Neuron projection development | 0.0431 | EHD1, GDNF, SHC1, STMN2, FYN | 3.78 |
| 0007411 | Axon guidance | 0.0508 | KLF7, GAP43, MYCBP2, PAX6, ANK3 | 3.58 |
| Immune related | ||||
| 0050729 | Positive regulation of inflammatory response | 0.0355 | CEBPA, CD47, LDLR, CX3CL1 | 5.53 |
| 0071560 | Cellular response to transforming growth factor beta stimulus | 0.0003 | ZEB1, NOX4, FYN, WNT2, TGFBR1, WNT4 | 10.39 |
| 0036120 | Cellular response to platelet-derived growth factor stimulus | 0.0152 | PRKCE, RASA1, FYN | 15.78 |
| Epithelial related | ||||
| 0010634 | Positive regulation of epithelial cell migration | 0.0373 | ITGA3, PRKCE, PPM1F | 9.77 |
| 0050680 | Negative regulation of epithelial cell proliferation | 0.0279 | ZEB1, CELF1, PAX6, MTSS1 | 6.08 |