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RBPs involved in nuclear export of pre-miRNA. (A) Canonical pre-miRNA nuclear export complex: Exportin five accommodates pre-miRNA in a deep pocket, and associates with RAN-GTP to facilitate transport through the nuclear pore complex. (B) Non-canonical m7G cap dependent pre-miRNA nuclear export complex: CBC recognizes the m7G cap, associated with Exportin 1-RAN-GTP through PHAX bridge.
