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. 2024 Mar 18;4(3):100733. doi: 10.1016/j.crmeth.2024.100733

Figure 4.

Figure 4

Benchmark results of fusion gene detection using bRNA-seq of cancer cell lines for 5 different tools

Each tool detects the supporting evidences of fusion genes using real cell line transcriptome data. The x axis represents the number of transcripts (in millions), and the labels correspond to subsampling ranges of 01128, respectively.

(A)–(F) correspond to the detection results of a specific fusion gene in the cell line, and the fusion breakpoints are annotated with GRCh38. The left section of the subgraph depicts all support evidences, and the y axis represents the logarithm base 2 of the quantity of evidences. The middle section corresponds to spanning evidences, while the right section represents split evidences. The y axis indicates the ratio of detected supporting evidences for each tool compared to the maximum supporting evidences among them.