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. 2024 Mar 19;11:1277818. doi: 10.3389/fmolb.2024.1277818

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Copyright © 2024 Ge, Cai, Cai, Mou, Fu and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Key genes analysis. (A–E) Differences in expression levels of BHLHE40 (A), MMP1 (B), NEAT1 (C), PPARG (D), and ADORA3 ^© in the control (green) and aortic dissection (AD, orange). (F–J) Receiver operating characteristic (ROC) curves for BHLHE40 (F), MMP1 (G), NEAT1 (H), ADORA3 (I), and PPARG (J). The horizontal coordinate is 1—specificity and the vertical coordinate is sensitivity. AUC, area under the curve. (K) Functional similarity analysis of key genes. (ns: p > 0.05, *: p < 0.05, **: p < 0.01, ***: p < 0.001, ****: p < 0.0001); the closer the AUC of the ROC curve is to 1, the better the diagnosis prediction (AUC of 0.5–0.7 indicates low accuracy, AUC of 0.7–0.9 indicates moderate accuracy, and AUC > 0.9 indicates high accuracy).