TABLE 2.
GO and KEGG enrichment analysis results of PREDGs.
| ONTOLOGY | ID | Description | P-value | q value |
|---|---|---|---|---|
| BP | GO:0050727 | Regulation of inflammatory response | 4.3701E-10 | 4.1631E-07 |
| BP | GO:0032103 | Positive regulation of response to external stimulus | 2.5777E-08 | 1.2278E-05 |
| BP | GO:0031349 | Positive regulation of defense response | 3.6163E-07 | 0.00011483 |
| CC | GO:0061702 | Inflammasome complex | 0.00036483 | 0.02162214 |
| CC | GO:0030667 | Secretory granule membrane | 0.00141337 | 0.02162214 |
| CC | GO:0034774 | Secretory granule lumen | 0.00158686 | 0.02162214 |
| MF | GO:0070851 | Growth factor receptor binding | 7.322E-05 | 0.00547222 |
| MF | GO:0005172 | Vascular endothelial growth factor receptor binding | 0.00023078 | 0.00662694 |
| MF | GO:0046965 | Nuclear retinoid X receptor binding | 0.00026601 | 0.00662694 |
| KEGG | hsa05323 | Rheumatoid arthritis | 0.00188382 | 0.08307365 |
| KEGG | hsa04015 | Rap1 signaling pathway | 0.00216219 | 0.08307365 |
| BP | GO:0050729 | Positive regulation of inflammatory response | 3.6817E-06 | 0.00087682 |
| BP | GO:0050673 | Epithelial cell proliferation | 6.1995E-06 | 0.0011227 |
| BP | GO:0051090 | Regulation of DNA-binding transcription factor activity | 7.0712E-06 | 0.0011227 |
| BP | GO:0032602 | Chemokine production | 1.9606E-05 | 0.00264818 |
| BP | GO:0002573 | Myeloid leukocyte differentiation | 2.2239E-05 | 0.00264818 |
GO, Gene Ontology; BP, biological process; CC, cellular component; MF, molecular function; KEGG, Kyoto Encyclopedia of Genes and Genomes; PRDEGs, Pyroptosis-related differentially expressed genes.