Evaluation
(A) Mean vs. standard deviation of the transcript counts are plotted for the “Swimming Downstream” and GTEx experiment samples to represent relative dispersion levels.
(B) Gene-level DTU performance evaluation on the “Swimming Downstream” dataset.
(C) Gene-level DTU performance evaluation on GTEx experiments. Error bars indicate the minimum and maximum FDR/TPR values obtained.
(D) Gene-level DTU performance evaluation on the satuRn (GTEx, 50 vs. 50) simulation.
(E) The DTU event sharing Venn diagram for the first experiment in the GTEx simulations (right), and the corresponding final subcluster dendrogram based on the SPIT DTU matrix (left). The subclusters are color coded based on their distinct sets of simulated DTU events (spliceotypes).