Figure 5.

Inflammatory and metabolic pathways are enriched in pre-implantation endometrial macrophages, while interferon-stimulated, hypoxia, and inflammatory response genes are enriched in first trimester decidual macrophages. (A) Bar graph showing absolute number of significant differentially expressed genes (DEGs) between indicated endometrial and first trimester decidual macrophage subclusters. Significant genes are defined as having an adjusted p value of <0.05 and an absolute fold change of 25% or greater (either ≥25% enriched in fresh or ≥25% in frozen). (B) Gene ontology (GO) analysis of DEGs enriched in indicated endometrial (black) or first trimester decidual (blue) macrophage superclusters. Detailed information describing the GO term enrichment bar graphs is provided in the caption to Figure 4B .