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. 2023 Oct 26;109(4):1247–1252. doi: 10.3324/haematol.2023.282914

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Figure 1. — Results of meta-analysis combining the TCCSG and JPLSG genome-wide association analysis results. (A) The Manhattan plot shows the -log10 (P value) of the logistic regression analysis plotted against the chromosomal position (GRCh37/ hg19). The blue line indicates the genome-wide significant P value threshold of 5x10^-8, and the dotted line was the threshold (1x10^-6) for considering results as suggestive. (B) A quantile-quantile plot of the observed versus expected distribution of the -log10 (P value) from the analysis. TCCSG: Tokyo Children Cancer Study Group; JPLSG: Japanese Pediatric Leukemia/Lymphoma Study Group.