Figure 2.
High-risk mantle cell lymphoma is enriched for MYChigh tumors. (A) Heatmap representing the distribution of patients with high and low MYC protein expression, TP53 mutation/p53 expression, morphology variant, proliferation (Ki-67) and age at diagnosis. (B) Association between age at diagnosis and MYChigh tumors. (C) Association between total percentage of MYC-positive cells and TP53/p53 status. Wilcoxon and t-test P values were used to evaluate statistical significance, and P values are shown. WT: wild-type; MIPI: Mantle cell lymphoma International Prognostic Index.