Table 3. Diagnostic tests used to detect Wilson’s disease patients in South Korea.
| Diagnostic tests | Total incident cases during the study period (N = 622) | Men (n = 340) | Women (n = 282) | Age at the first diagnostic test (years old) | |
|---|---|---|---|---|---|
| Serum ceruloplasmin | 615 (98.9) | 336 (98.8) | 279 (98.9) | 22.0 ± 17.7 | |
| Copper quantification | |||||
| Serum or 24 hr-urinary excretion | 607 (97.6) | 333 (97.9) | 274 (97.2) | 21.7 ± 17.4 | |
| Tissue | 87 (14.0) | 55 (16.2) | 32 (11.3) | 22.8 ± 16.5 | |
| Slit lamp test | 588 (94.5) | 318 (93.5) | 270 (95.7) | 17.0 ± 16.8 | |
| ATP7B genotyping | 162 (26.0) | 92 (27.1) | 70 (24.8) | 22.0 ± 17.9 | |
| Biopsy | 321 (51.6) | 175 (51.5) | 146 (51.8) | 26.8 ± 18.2 | |
| Brain/hippocampus MRI | 181 (29.1) | 101 (29.7) | 80 (28.4) | 29.7 ± 18.6 | |
| Abdominal ultrasonography | 455 (73.2) | 243 (71.5) | 212 (75.2) | 23.3 ± 17.0 | |
Values are presented as number (%) or mean ± standard deviation.
MRI = magnetic resonance imaging.