Table 5.
Statistical analysis of the top 15 features between the single correct prediction patients and the multiple prediction patients in the MIMIC-IVa validation populations.
| Variables | Survivors | Nonsurvivors |
|
|||||
| Single correct (n=2123) | Multiple (n=1012) | P value | Single correct (n=397) | Multiple (n=217) | P value | P valueb | ||
| APS IIIc (score), median (IQR) | 39 (31-49) | 55 (44-66) | <.001 | 78 (64-94) | 58 (47-68) | <.001 | .05 | |
| Age (years), median (IQR) | 64 (54-74) | 72 (61-82) | <.001 | 71 (59-82) | 75 (60-81) | .40 | .57 | |
| Urine output (mL), median (IQR) | 1900 (1310-2675) | 1350 (808-2065) | <.001 | 635 (206-1171) | 1278 (845-1815) | <.001 | .31 | |
| Vasopressor, n (%) | 959 (45.2) | 520 (51.4) | .01 | 347 (87.4) | 134 (61.8) | <.001 | .005 | |
| Pulmonary infection, n (%) | 585 (27.6) | 603 (59.6) | <.001 | 230 (57.9) | 127 (58.5) | .89 | .77 | |
| Lactate (min) (mmol/L), median (IQR) | 1.2 (1.0-1.6) | 1.4 (1.1-1.9) | <.001 | 2.2 (1.5-3.4) | 1.4 (1.1-1.9) | <.001 | .72 | |
| BMI (kg/m2), median (IQR) | 27.8 (24.5-32.3) | 26.5 (23.0-30.8) | <.001 | 26.8 (23.5-32.3) | 25.9 (23.2-31.4) | .57 | .61 | |
| WBCd count (min) (K/μL), median (IQR) | 9.2 (6.6-12.1) | 9.9 (6.8-14.0) | <.001 | 11.7 (7.0-16.4) | 10.4 (6.6-14.4) | .06 | .50 | |
| SpO2e (std) (%), median (IQR) | 1.86 (1.36-2.39) | 1.93 (1.34-2.55) | .08 | 2.45 (1.71-3.46) | 2.12 (1.43-2.89) | <.001 | .01 | |
| PLTf count (max) (K/μL), median (IQR) | 204 (153-269) | 213 (147-286) | .11 | 198 (128-298) | 205 (137-279) | .91 | .20 | |
| Respiratory rate (mean) (bpm), median (IQR) | 18 (16-21) | 20 (17-22) | <.001 | 22 (19-25) | 20 (17-23) | <.001 | .22 | |
| Serum anion gap (min) (mmol/L), median (IQR) | 12 (10-14) | 13 (11-16) | <.001 | 15 (13-19) | 13 (11-16) | <.001 | .34 | |
| BUNg (min) (mg/dL), median (IQR) | 16 (12-24) | 25 (16-41) | <.001 | 33 (19-50) | 27 (17-42) | .006 | .43 | |
| aPTTh (max) (s), median (IQR) | 32.3 (28.3-39.2) | 33.8 (29.0-44.5) | <.001 | 44.9 (33.1-64.3) | 34.4 (28.4-47.1) | <.001 | .83 | |
| Serum sodium (max) (mmol/L), median (IQR) | 140 (138-142) | 140 (137-144) | .28 | 140 (136-144) | 140 (136-143) | .98 | .54 | |
aMIMIC-IV: Medical Information Mart for Intensive Care database-IV.
bStatistical analysis between survival and nonsurvival multiple predictions.
cAPS III: Acute Physiology Score III.
dWBC: white blood cell.
eSpO2: oxygen saturation.
fPLT: platelet.
gBUN: blood urea nitrogen.
haPTT: activated partial thromboplastin time.