TABLE 2.
Subpopulation analysis of the strains that showed discrepancies between the estimation of mutations of nucleotides at positions 2058 and 2059 in the domain V region of the 23S rRNA gene and results of ARMS–LAMP analysisa
| Strain | Total number |
MIC (µg/mL) |
Genotype | ARMS–LAMP | ||||
|---|---|---|---|---|---|---|---|---|
| WTPS | CA-MTPS | GA-MTPS | TA-MTPS | AC-MTPS | ||||
| AV-27 | 3 | <8 | AA | + | – | |||
| AV-47 | 3 | >32 | CA | + | – | |||
| AV-124 | 3 | >32 | AC | – | + | |||
| AV-207 | 3 | >32 | TA | + | + | |||
| AV-392 | 3 | >32 | TA | + | + | |||
a
AC-MTPS, A2059C mutant-type mismatch primer set; ARMS–LAMP, amplification refractory mutation system–loop-mediated isothermal amplification; CA-MTPS, A2058C mutant-type mismatch primer set; GA-MTPS, A2058G mutant-type mismatch primer set; TA-MTPS, A2058T mutant-type mismatch primer set; WTPS, wild-type mismatch primer set.