TABLE 4.
Acquired β-lactamase genes identified in meropenem-resistant Acinetobacter spp. isolates (n = 227)a,b
| Isolate | β-Lactamase group | Total | |||||
|---|---|---|---|---|---|---|---|
| OXA | OXA + MBL | OXA + ESBL | MBL | ESBL + KPC | Negative | ||
| A. baumannii | 156 | 8 | 3 | 3 | 1 | 6 | 177 |
| A. baumannii complex | 32 | – | – | – | – | 2 | 34 |
| A. bereziniae | 1 | – | – | – | – | – | 1 |
| A. nosocomialis | 1 | – | – | – | – | – | 1 |
| Other Acinetobacter spp. | 12 | 1 | 1 | – | – | – | 14 |
| Total | 202 | 9 | 4 | 3 | 1 | 8 | 227 |
a
ESBL, extended-spectrum β-lactamase; KPC, Klebsiella pneumoniae carbapenemase; MBL, metallo-β-lactamase; OXA, oxacillinase; PCR, polymerase chain reaction; WGS, whole-genome sequencing.
b
Data were generated by WGS if meropenem-resistant isolates were resistant to cefiderocol (174/227, including 1 A. baumannii complex and 4 other Acinetobacter spp.) or PCR if isolates were susceptible to cefiderocol (53/227, including 33 A. baumannii complex and 10 other Acinetobacter spp.). Isolates are grouped as “negative” if only intrinsic β-lactamase genes were present (n = 1) or if no screened β-lactamase gene was present (n = 7).