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. Author manuscript; available in PMC: 2024 Apr 2.

Published in final edited form as: Gastroenterology. 2023 Apr 5;165(1):201–217. doi: 10.1053/j.gastro.2023.03.228

Figure 7. — Spp1^{KI Mye} and WT mice were fed for 6 months with control or NASH-inducing diet. (A) Body weight change throughout the experiment. (B) Average amount of food intake throughout the experiment. (C) Final body weight before euthanasia, and VAT-to-body weight ratio. (D) H&E staining of adipose tissue (green arrows: adipocytes). (E) Relative mRNA expression of Pnpla2, Lipe, Leptin and AdipoQ in adipose tissue. (F) In vivo lipolysis analysis measuring serum NEFA concentration after injection of isoproterenol (n=4–5/group). (G) GTT and ITT (n=4/group). Results are expressed as mean ± SEM; n=6/group. *p<0.05, **p<0.01 and ***p<0.001 vs. WT with same diet.

Figure 7. — Spp1^{KI Mye} and WT mice were fed for 6 months with control or NASH-inducing diet. (A) Body weight change throughout the experiment. (B) Average amount of food intake throughout the experiment. (C) Final body weight before euthanasia, and VAT-to-body weight ratio. (D) H&E staining of adipose tissue (green arrows: adipocytes). (E) Relative mRNA expression of Pnpla2, Lipe, Leptin and AdipoQ in adipose tissue. (F) In vivo lipolysis analysis measuring serum NEFA concentration after injection of isoproterenol (n=4–5/group). (G) GTT and ITT (n=4/group). Results are expressed as mean ± SEM; n=6/group. *p<0.05, **p<0.01 and ***p<0.001 vs. WT with same diet.