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tPA shRNA treatment after reperfusion decreases acute brain damage in both sexes of stroke-induced rats. Representative TTC stained images of untreated and tPA shRNA treated male and female rat brain coronal sections one day after a 1.5-h focal cerebral ischemia. The column scatter plot shows the quantified percent infarct volume in various experimental groups. Columns indicate the mean and error bars indicate the SEM. *p < 0.05 vs untreated group.
