Table 1.
Baseline clinical and laboratory features of patients with COVID-19.
|
Variables |
Results n (%) |
|---|---|
|
Age (years), median (IQR) |
48 (27; range=21-92) |
|
Gender (Female) |
56 (60.9) |
|
Symptoms | |
|
Fever (n=81) |
24 (26.1) |
|
Dyspnea (n=82) |
39 (47.6) |
|
Cough (n=83) |
47 (56.6) |
|
Headache (n=81) |
13 (16) |
|
Fatigue (n=83) |
48 (57.8) |
|
Diarrhea (n=83) |
8 (9.6) |
|
Comorbidities | |
|
Hypertension (n=83) |
26 (31.3) |
|
Diabetes mellitus (n=85) |
19 (22.4) |
|
COPD (n=85) |
2 (2.4) |
|
Asthma (n=84) |
11 (13.1) |
|
CAD (n=84) |
6 (7.1) |
|
Heart failure (n=80) |
4 (5) |
|
Chronic kidney failure (n=78) |
2 (2.6) |
|
Oxygen saturation (n=92) (mean±SD) |
92.1 ± 3.8 (range=84-98) |
|
Oxygen saturation (<90) |
21 (23) |
|
COVID-19 disease severity | |
|
NIH score 2 |
48 (52.2) |
|
NIH score 3 |
44 (47.8) |
|
ICU admission |
2 (2.1) |
|
Exitus |
1 (1) |
|
Laboratory parameters | |
|
Leucocyte count, median (IQR) |
5810 (2268) |
|
Lymphocyte count, median (IQR) |
1135 (750) |
|
Neutrophil count, median (IQR) |
4005 (2283) |
|
Hemoglobin (g/dL), median (IQR) |
14 (4) |
|
Platelets, median (IQR) |
180,000 (91,250) |
|
CRP (mg/L), median (IQR) |
48.8 (100) |
|
Ferritin (ng/mL), median (IQR) |
128 (259) |
|
D-dimer (mcg/mL), median (IQR) |
657 (593) |
|
KL-6 (U/mL), median (IQR) |
54.1 (29.1) |
|
AST (U/L), median (IQR) |
31.5 (23) |
|
ALT (U/L), median (IQR) |
23.5 (24) |
|
GGT (U/L), median (IQR) |
37 (41) |
|
LDH (U/L), mean ± SD |
290±98 |
|
NLR, median (IQR) |
3.3 (3) (range=0.7-21.9) |
|
NLR | |
|
<10 |
85 (92.4) |
|
≥10 |
7 (7.6) |
|
cHIS score, median (IQR) |
1 (1) (range=0-4) |
|
cHIS score | |
|
<2 |
75 (81.5) |
|
≥2 |
17 (18.5) |
|
Treatment | |
|
Favipiravir |
82 (89.1) |
|
Low-molecular-weight heparin |
88 (95.7) |
|
Steroids |
72 (78.3) |
|
Antibiotics | |
|
Fluoroquinolone |
72 (78.3) |
|
Ceftriaxone |
41 (44.6) |
|
Piperacillin-tazobactam |
8 (8.7) |
|
Meropenem |
1 (1.1) |
SD: Standard deviation, IQR: Interquartile range, COPD: Chronic obstructive pulmonary disease, CAD: Coronary artery disease, NIH: National Institute of Health, CRP: C-reactive protein, KL-6: Krebs von den Lungen-6, AST: Aspartate aminotransferase, ALT: Alanine aminotransferase, GGT: Gamma-glutamyl transferase, LDH: Lactate dehydrogenase, NLR: Neutrophil-to-lymphocyte ratio, cHIS: COVID-19 hyperinflammatory syndrome score.