Table 2.
Univariate analysis of KL-6 levels according to different clinical and laboratory parameters*.
|
Variables |
KL-6 |
|
|---|---|---|
|
median (IQR) |
p |
|
|
Age (years) | ||
|
<60 |
54.1 (28.6) |
0.9 |
|
≥60 |
54.8 (27.4) |
|
|
Gender | ||
|
Male |
54.2 (25.1) |
0.8 |
|
Female |
53.7 (31.7) |
|
|
Comorbidities | ||
|
Hypertension |
||
|
Yes |
52.6 (24.7) |
0.6 |
|
No |
54.5 (31.5) |
|
|
Diabetes mellitus |
||
|
Yes |
59.3 (44.7) |
0.036 |
|
No |
52.7 (24.8) |
|
|
Oxygen saturation |
||
|
<90 |
48.6 (48.5) |
0.6 |
|
≥90 |
52.7 (22.1) |
|
|
COVID-19 disease severity, n (%) | ||
|
NIH score 2 |
56.9 (25.6) |
0.15 |
|
NIH score 3 |
50.7 (28.8) |
|
|
Lymphocyte count, mm3/L | ||
|
<1000 |
49.7 (23.1) |
0.06 |
|
>1000 |
57.6 (32) |
|
|
cHIS score | ||
|
<2 |
52.7 (29.1) |
0.077 |
|
≥2 |
61.7 (32.2) |
|
IQR:Interquartile range, NIH:National Institute of Health, KL-6:Krebs von den Lungen-6, cHIS:COVID-19 hyperinflammatory syndrome score.
*Normal distribution was assessed using the Kolmogorov-Smirnov test. Non-normally distributed continuous numerical data were compared with the Mann-Whitney U test.