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| Location | Pop. | Pre-PCV | Post-PCV | Decrease in incidence rate | ||
|---|---|---|---|---|---|---|
| Time interval | Incidence (per 100,000) | Time interval | Incidence rate (per 100,000) | |||
| Iceland [26] | 0–47 months | 2005–2013 (pre PCV10) | 232 | 2011–2018 (post PCV10) | 145 | 38% |
| Italy, Apulia region [55] | <60 months | 2001–2005 (pre PCV7) | 205 | 2006–2011 (post PCV7) | 154.7 | 25% |
| Italy (8 first regions to introduce PCVs) [56] | 91 | 58.9 | 35% | |||
| Italy [56] | 100 | 61.3 | 39% | |||
